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 Genetically Engineered Stem Cells Support Nerve Regeneration

NEKO Alapítványszjozsi writes "Genetically Engineered Stem Cells Support Nerve Regeneration

Gabe Romain
Betterhumans Staff
Tuesday, October 21, 2003, 6:22:01 PM CT


http://www.betterhumans.com/News/news.aspx?articleID=2003-10-21-5

A finding about how genetically engineered stem cells heal damaged nerve fibers months after an injury has provided further evidence that stem cells release therapeutic molecules that can help treat spinal cord damage.

Researchers from Johns Hopkins University School of Medicine in Baltimore, Maryland report that nerves of injured rats regenerated as much as six months after treatment with modified stem cells from mice.

"This is the first demonstration of regeneration in chronically denervated nerves," says Ahmet Hoke of Johns Hopkins.

"

Posted by administrator on Szerda, október 22 @ 19:18:10 CEST (885 reads)
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 Samuil Rabinovich's Fetal cell transplantation

NEKO Alapítványszjozsi writes "Samuil Rabinovich's Fetal cell transplantation

 

The cells from fetal nervous and hemopoietic tissues (gestational age 16-22 weeks) were subarachnoidally implanted into 15 patients of 18-to-52 year old with severe consequences of the traumatic spinal cord injure (SCI) at cervical or thoracic spine level. The times after SCI were from 1 month to 6 years. The number of fetal cell transplantations (FCT) into a patient varied from 1 to 4. The time intervals between FCT were 14-to-30 days. In 11 of 15 cases FCT was performed immediately after resection of the connective tissue cyst(s) that has been formed within the site of SCI. Before FCT the neurological state of each of the patients was characterized by complete motor and sensory function disorder and was consistent with a grade A of SCI according to Frankel classification. With FCT therapy, the neurological state of 6 patients became clinically consistent with C grade of SCI. These patients received an ability to walk with the aid of crutches or a special hinged apparatus. The less, although noticeable, clinical improvements were noted in other 5 FCT-treated patients. Their state became consistent with grade B of SCI and was characterized by appearance of contracting activity in some muscles and incomplete restoration of sensitivity. Lastly, 4 patients subjected to FCT therapy did not demonstrate any clinical improvements. No serious complications of FCT were noted. The results presented herein point out a clinical relevance of the FCT-based approach to treating severe consequences of SCI.

"

Posted by administrator on Szerda, október 22 @ 19:16:46 CEST (6514 reads)
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 New hope for the paralysed as scientists re-grow spinal cords

NEKO Alapítványszjozsi writes "New hope for the paralysed as scientists re-grow spinal cords (Filed: London Telegraph 13/07/2003)

Thirty years of research culminate in a 'Eureka!' moment for a French biologist working to regenerate severed nerve endings, reports Kim Willsher in Paris.

"

Posted by administrator on Csütörtök, október 09 @ 16:50:24 CEST (6140 reads)
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 SCIENTISTS USE A VARIETY OF CELLS AND MOLECULES TO COAX REGROWTH OF DAMAGED NERV

NEKO Alapítványszjozsi writes "SCIENTISTS USE A VARIETY OF CELLS AND MOLECULES TO COAX REGROWTH OF DAMAGED NERVES.

ORLANDO, Sunday, Nov. 3 - Step by step, scientists are making new advances in regenerating damaged nerves and nerve fibers - advances that may one day help people who have conditions or diseases in which nerve cells have become impaired or have ceased functioning entirely, including spinal cord injuries, blindness, stroke and multiple sclerosis.

"

Posted by administrator on Csütörtök, október 09 @ 16:48:24 CEST (5897 reads)
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